Human receptor tyrosine kinases

ALK family
ALK Ki1 NM_004304 NP_004295 2p23
LTK TYK1 NM_002344 NP_002335 15q15.1-q21.1

AXL family
AXL UFO, Tyro7(r) Ark(m) NM_001699 NP_001690 19q13.1
MER MERTK, NYK, Eyk(ch) NM_006343 NP_006334 2q14.1
TYRO3 RSE, SKY, BRT, DTK, TIF NM_006293 NP_006284 15q15.1-q21.1

DDR family
DDR1 CAK, TRKE, NEP, NTRK4,EDDR1, PTK3 NM_013993 NP_001945 6p21.3
DDR2 TKT, TYRO10, NTRKR3 NM_006182 NP_006173 1q21-q22

EGFR family
EGFR ERBB, ERBB1 NM_005228 NP_005219 7p12
ERBB2 HER2, Neu(r), NGL NM_004448 NP_004439 17q11.2-q12
ERBB3 HER3 NM_001982 NP_001973 12q13
ERBB4 HER4 NM_005235 NP_005226 2q33.3-q34

EPH family
EPHA1 EPH, EPHT NM_005232 NP_005223 7q32-q36
EPHA2 ECK, Sek2(m), Myk2(m) NM_004431 NP_004422 1p34
EPHA3 HEK, ETK1, Tyro4(r), Mek4(m),Cek4(ch) NM_005233 NP_005224 3p11.2
EPHA4 HEK8, Tyro1(r), Sek1(m), Cek8(ch) NM_004438 NP_004429 2q36-qter
EPHA5 HEK7, Ehk1(r), Bsk(r), Cek7(ch) L36644 P54756
EPHA6 DKFZp434C1418, Ehk2(r) AL133666
EPHA7 HEK11, Mdk1(m), Ebk(m),Ehk3(r), Cek11(ch) NM_004440 NP_004431 6q21
EPHA8 HEK3, KIAA1459, Eek(r), Cek10(ch) AB040892 CAB81612 1q23-q24
EPHB1 NET, EPHT2, HEK6, Elk(r), Cek6(ch) NM_004441 NP_004432 3q21-q23
EPHB2 HEK5, ERK, DRT, EPHT3, Tyro5(r),Nuk(m), Sek3(m), Cek5(ch) AF025304 AAB94602 1p36.1-p35
EPHB3 HEK2, Tyro6, Mdk5(m), Sek4(m) NM_004443 NP_004434 3q21-qter
EPHB4 HTK, Tyro11(r), Mdk2(m), Myk1(m) NM_004444 NP_004435
EPHB6 HEP, Mep(m), Cek1(ch) NM_004445 NP_004436 7q33-q35
EPHX AC023225 1

FGFR family
FGFR1 FLT2, bFGFR, FLG, N-SAM M34641 AAA35835 8p11.2
FGFR2 KGFR, K-SAM, Bek(m), CFD1,JWS, Cek3(ch) NM_000141 NP_000132 10q26
FGFR3 HBGFR, ACH, Cek2(ch) NM_000142 NP_000133 4p16.3
FGFR4 NM_002011 NP_002002 5q35.1-qter

INSR family
IGF1R JTK13 NM_000875 NP_000866 15q25-q26
INSR IR NM_000208 NP_000199 19p13.3-p13.2
INSRR IRR J05046 AAC31759 1q21-q23

MET family
MET HGFR NM_000245 NP_000236 7q31
RON MST1R, CDw136, Fv2(m),STK(m), SEA(ch) NM_002447 NP_002438 3p21.3

MUSK family
MUSK Nsk2(m), Mlk1(m), Mlk2(m) NM_005592 NP_005583 9q31.3-q32

PDGFR family
CSF1R FMS, C-FMS, CD115 NM_005211 NP_005202 5q31-q32
FLT3 FLK2, STK1, CD135 NM_004119 NP_0041110 13q12
KIT Sfr(m), CKIT NM_000222 NP_000213 4q11-q12
PDGFRA NM_006206 NP_006197 4q11-q13
PDGFRB PDGFR, JTK12 NM_002609 NP_002600 5q31-q32

PTK7 family
PTK7 CCK4, KLG(ch) NM_002821 NP_002812 6p21.1-p12.2

RET family
RET MEN2A/B, HSCR1, MTC1 X12949 P07949 10q11.2

ROR family
ROR1 NTRKR1 NM_005012 NP_005003 1p32-p31
ROR2 NTRKR2 NM_004560 NP_004551

ROS family
ROS1 MCF3 NM_002944 NP_002935 6q22

RYK family
RYK Vik(m), Mrk(m) S59184 AAB26341 3q22

TIE family
TEK TIE2 NM_000459 NP_000450 9p21
TIE TIE1, JTK14 NM_005424 NP_005415 1p34-p33

TRK family
NTRK1 TRK, TRKA NM_002529 NP_002520 1q21-q22
NTRK2 TRKB NM_006180 NP_006171 9q22.1
NTRK3 TRKC NM_002530 NP_002521 15q25

VEGFR family
VEGFR1 FLT1 NM_002019 NP_002010 13q12
VEGFR2 KDR, FLK1 AAB88005 4q11-q12
VEGFR3 FLT4, PCL NM_002020 NP_002011 5q34-q35

AATYK family
AATYK AATK, KIAA0641 NM_004920 NP_004911 17q25.3
AATYK2 KIAA1079 NM_014916 NP_055731 7q21-q22
AATYK3 AC008403 19q13.2-q13.3




Reference : The Protein tyrosine kinase family of the human genome, Dan R Robinson, Yi-Mi Wu and Su-Fang Lin, Oncogene(2000) 19, 5548-5557.